Rewiring Maladaptive Reward Learning using Dimethyltryptamine
28 August 2024
We are conducting a brain imaging study to look at how the psychedelic drug, N,N-Dimethyltryptamine (DMT) enhances neuroplasticity compared to other plasticity-enhancing drugs. This will involve comparing the activity in your brain using functional magnetic resonance imaging (fMRI) while watching movies. We will also use electroencephalography (EEG) to look at your brain activity while under the effects of either DMT, Lisuride, D-Cycloserine or placebo.
Requirements
- Aged 21- 65
- Drink alcohol regularly and want to cut down
- No diagnosis of alcohol use disorder
- Can attend UCL on 3 separate occasions (within a 4 week period)
- Happy to receive an intravenous dose of DMT, Lisuride, D-Cycloserine or placebo
- Can commit to attending follow-up sessions at 1-month, 3-months, 6-months and 9-months.
Keywords
Ethical approval
This study has been approved by the University College London ethics committee (Ethics ID number: 17715/001).
