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Ageing in the Immune System

17 September 2024

Immunity declines with age, leading to higher risks of diseases, weaker responses to new infections, and reduced vaccine efficacy. Our research aims to understand the mechanisms behind this decline by studying changes in the aging immune system. We analyze peripheral blood to assess differences in the functional, metabolic, and migratory profiles of immune cells between young and elderly individuals. Insights from this research could inform the development of new drugs to boost the immune system

Requirements

  • - Age below 35 or over 65
  • - Both males and females
  • - Non-smoker
  • - No history of autoimmune disease

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Ethical approval

The study has been approved by University College London. Prior to participation, all participants will be provided with a participant information sheet and, if they agree to take part, will be required to sign a consent form.

About the researcher

My name is Polina Deletic, and I am a final-year PhD student at University College London in Professor Arne Akbar's lab. Professor Akbar is a pioneer in ageing research. He and his team have been working in the field for over 40 years and have conducted multiple human studies. Their results have been published in high-impact, peer-reviewed journals.

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