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CODA Study: Comorbid Obesity & Depression with Anti-inflammatory Medication

01 October 2024

Are you living with obesity and currently taking antidepressant medication that you feel isn’t really helping?

Researchers at King’s College London are investigating how an anti-inflammatory medication called minocycline can work as an antidepressant in some people with depression – and we need your help.

Participants can earn up to £90 for their time. An additional £40 can be earned for completing the 2 optional MRI brain scans.

Requirements

  • Aged 18 or older.
  • Current diagnosis of depression.
  • Living with obesity (i.e., a body mass index equal to 30kg/m2 or higher).
  • Currently taking an anti-depressant medication.
  • Felt insufficient response to two other anti-depressant medications.
  • Not currently taking antibiotics, antipsychotics, blood thinners, or anti-inflammatory medications.
  • Able to take minocycline for 8 weeks
  • (optional) Able to undergo 2 MRI brain scans.

Take part in this study

Keywords

Ethical approval

This study received a favourable opinion from the East of England – Cambridge Central REC (24/EE/0134) on 30th July 2024.

Contact researcher

Academic study
 

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